Should the Prolotherapy patient take anti-inflammatory medications for pain relief of established joint pain and post-therapeutic pain?

For the relief of established joint pain or post-therapeutic pain, DO NOT use any steroidal or nonsteroidal anti-inflammatory drugs (see list below)–neither prescribed, over-the-counter, oral, or injection–for two weeks prior to prolotherapy treatment and

four weeks following prolotherapy treatment.
Anti-inflammatory drugs include:

  • Steroidal drugs such as cortisone and prednisone and
  • Nonsteroidal drugs such as Advil, Alka Seltzer, Anaprox, Artrotec, Aspirin (acetylsalicylic acid), Bristel, Cataflam, Celebrex, Clinoril, Ecotrin, Excedrin, Feldene, Indocine, Lodine, Motrin (Ibuprofen), Naprosyn, Percodan, Vioxx, any Cox-2 inhibitors, or white willow bark derivatives.
  • Note: 80 mg of Aspirin a day for cardiovascular protection is acceptable.

For pain relief following Prolotherapy, the only acceptable analgesic drugs are those that are NOT anti-inflammatory. These include:

  • Over-the-counter drugs such as Tylenol (acetaminophen) or
  • Prescribed Class II medications, such as codeine (e.g., Tylenol 3) or hydrocordone (e.g., Lorcet or Vicodin) or oxycodone (e.g., Percocet).

You are to follow the dosage directions as prescribed. Do not use additional dosages or medications without Dr. Clark’s personal permission.
Also, DO NOT APPLY ICE, which is anti-inflammatory, at any time during the course of Prolotherapy.