Is smoking a contraindication to receiving Prolotherapy?

Smoking cigarettes or any other tobacco nicotine source (e.g., pipe, cigar, snuff) significantly impedes the therapeutic (healing) effectiveness of Prolotherapy. 

Subsequently, if the patient uses nicotine and chooses to pursue a series of Prolotherapy sessions, it is understood that the patient runs the risk of experiencing either delayed healing (requiring more than the statistical average number of sessions), incomplete healing, or no healing at all.