Is Prolotherapy painful?

Injection of the proliferant solution may cause some short-lived pain since the ligaments or tendons are injured and are already tender to needle point.

This discomfort is only momentary. Post-therapeutically, the inflammatory reaction may produce a dull, achy discomfort, which lasts only one to three days. Generally, the discomfort of Prolotherapy is over rated, especially when measured against its long-standing, beneficial therapeutic effects.